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Bjorn R Olsen Selected Research

Cherubism

9/2014Enhanced TLR-MYD88 signaling stimulates autoinflammation in SH3BP2 cherubism mice and defines the etiology of cherubism.
5/2012The role of SH3BP2 in the pathophysiology of cherubism.
12/2011Tankyrase loses its grip on SH3BP2 in cherubism.
11/2008NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.
1/2007Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice.

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Bjorn R Olsen Research Topics

Disease

11Neoplasms (Cancer)
03/2015 - 05/2002
7Hemangioma (Angioma)
01/2016 - 11/2008
5Inflammation (Inflammations)
10/2016 - 01/2007
5Hypoxia (Hypoxemia)
01/2016 - 05/2004
5Cherubism
09/2014 - 01/2007
5Knobloch syndrome
01/2010 - 04/2002
4Osteoarthritis
10/2017 - 01/2005
3Macular Degeneration (Age-Related Maculopathy)
12/2007 - 05/2004
3Choroidal Neovascularization
12/2007 - 05/2004
2Alzheimer Disease (Alzheimer's Disease)
01/2020 - 01/2019
2Skin Abnormalities
10/2017 - 03/2015
2Pseudoanodontia and Optic atrophy Alopecia Growth retardation
01/2016 - 03/2015
2Anodontia (Hypodontia)
01/2016 - 02/2004
2Osteoporosis
09/2012 - 11/2008
2Polycystic Kidney Diseases (Polycystic Kidney Disease)
06/2009 - 07/2008
2Bone Resorption
11/2008 - 06/2007
2Atrophy
08/2008 - 06/2002
2Hydrocephalus (Hydrocephaly)
05/2005 - 10/2003
1Mitochondrial Diseases (Mitochondrial Disease)
01/2019
1Wounds and Injuries (Trauma)
01/2016
1Burns
01/2016
1Heterotopic Ossification (Ectopic Ossification)
01/2016
1Synovitis
01/2016
1Pain (Aches)
01/2016
1Alopecia (Baldness)
01/2016
1Sclerosis
01/2016
1Optic Atrophy
01/2016
1Bone Cysts (Bone Cyst)
01/2016
1Osteophyte
01/2016
1Retinal Neovascularization
01/2016
1Calciphylaxis
08/2015
1Osteolysis
03/2015
1Fibrosis (Cirrhosis)
03/2015
1Hypertrophy
05/2012
1Dwarfism
05/2012
1Carcinogenesis
04/2010
1Neurodegenerative Diseases (Neurodegenerative Disease)
08/2009
1Diabetic Nephropathies (Diabetic Nephropathy)
07/2009
1Metabolic Bone Diseases (Osteopenia)
11/2008
1Pathologic Neovascularization
12/2007
1Arthritis (Polyarthritis)
03/2007
1Gout
03/2007

Drug/Important Bio-Agent (IBA)

14Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2017 - 11/2005
10EndostatinsIBA
04/2010 - 04/2002
8Proteins (Proteins, Gene)FDA Link
05/2012 - 03/2007
7Collagen Type XVIII (Type XVIII Collagen)IBA
01/2010 - 04/2002
4CollagenIBA
03/2015 - 06/2003
4Transcription Factors (Transcription Factor)IBA
11/2008 - 05/2003
3anthrax toxin receptorsIBA
01/2016 - 03/2007
3IntegrinsIBA
01/2016 - 11/2008
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2014 - 01/2007
2Amyloid beta-PeptidesIBA
01/2020 - 01/2019
2Messenger RNA (mRNA)IBA
01/2019 - 01/2012
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
03/2015 - 05/2009
2LigandsIBA
09/2014 - 03/2006
2Collagen Type VIIIIBA
07/2009 - 08/2005
2Discoidin Domain Receptor 2IBA
08/2007 - 01/2005
2Angiogenesis InhibitorsIBA
03/2004 - 05/2002
1Amyloid (Amyloid Fibrils)IBA
01/2019
1Flavin-Adenine Dinucleotide (FAD)IBA
01/2019
1RNA (Ribonucleic Acid)IBA
01/2019
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2016
1Activins (Activin)IBA
01/2016
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
01/2016
1Retinaldehyde (Retinal)IBA
01/2016
1ChemokinesIBA
01/2016
1MineralsIBA
08/2015
110-N-nonylacridinium orange (NAO)IBA
03/2015
1Biological ProductsIBA
05/2012
1Alkaline PhosphataseIBA
05/2012
1Sirolimus (Rapamycin)FDA Link
01/2012
1Small Interfering RNA (siRNA)IBA
01/2012
170-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
01/2012
1TankyrasesIBA
12/2011
1Epidermal Growth Factor (EGF)IBA
10/2009
1Streptozocin (Streptozotocin)FDA Link
07/2009
1Extracellular Matrix ProteinsIBA
07/2009
1Growth Factor ReceptorsIBA
05/2009
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
05/2009
1OsteoprotegerinIBA
11/2008
1AntibodiesIBA
11/2008
1Integrin beta1IBA
11/2008
1CytokinesIBA
11/2008
1Carrier Proteins (Binding Protein)IBA
11/2008
1Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
11/2008
1Vitamin DFDA LinkGeneric
08/2008
1Collagen Type II (Type II Collagen)IBA
07/2008
1Recombinases (Recombinase)IBA
07/2008
1Collagen ReceptorsIBA
08/2007
1urate transporterIBA
03/2007
1Calcium PyrophosphateIBA
03/2007
1Genetic Markers (Genetic Marker)IBA
03/2007
1Leucine (L-Leucine)FDA Link
03/2007
1Uric Acid (Urate)IBA
03/2007
1Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
03/2007

Therapy/Procedure

2Sutures (Suture)
06/2009 - 06/2007
2Therapeutics
03/2007 - 05/2002
1Immunotherapy
01/2020
1Distraction Osteogenesis
10/2016
1Tenotomy
01/2016